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Synthetic cannabis
Synthetic cannabis (synthetic marijuana), or technically synthetic cannabinoid receptor agonists are designer drugs that mimic the effects of cannabis sprayed onto a herbal base material. There are several psychoactive artificial cannabinoid families (e.g. AM-xxx, HU-xxx, JWH-xxx, CP xx) that are used as designer drugs sprayed on herbs and sold as natural highs under brand names like K2 and Spice,〔(【引用サイトリンク】title=What's the buzz?: Synthetic marijuana, K2, Spice, JWH-018 : Terra Sigillata )〕 both of which are genericized trademarks used for any synthetic cannabis product. Synthetic cannabis is often termed spice product.
When synthetic cannabis blends first went on sale in the early 2000s, it was thought that they achieved an effect through a mixture of natural herbs. Laboratory analysis in 2008 showed that this was not the case, and that they in fact contain synthetic cannabinoids that act on the body in a similar way to cannabinoids naturally found in cannabis, such as THC. A large and complex variety of synthetic cannabinoids, most often cannabicyclohexanol, JWH-018, JWH-073, or HU-210, are used in an attempt to avoid the laws that make cannabis illegal, making synthetic cannabis a designer drug. It has been sold under various brand names, online, in head shops, and other stores.
It is often marketed as "herbal incense"; however, some brands market their products as "herbal smoking blends". In either case, the products are usually smoked by users. Although synthetic cannabis does not produce positive results in drug tests for cannabis, it is possible to detect its metabolites in human urine. The synthetic cannabinoids contained in synthetic cannabis products have been made illegal in many European countries.
==Relationship to cannabis==
(詳細はwww.emed-journal.com ) Lapoint J, Nelson LS. Synthetic Cannabinoids: The Newest, Almost Illicit Drug of Abuse. Emergency Medicine 2011;43(2):26-28〕 Research on the safety of synthetic cannabinoids is now becoming available. Initial studies are focused on the role of synthetic cannabinoids in psychosis. Synthetic cannabis may precipitate psychosis and in some cases it may be prolonged. Some studies suggest that synthetic cannabinoid intoxication is associated with acute psychosis, worsening of previously stable psychotic disorders, and it may trigger a chronic (long-term) psychotic disorder among vulnerable individuals such as those with a family history of mental illness.〔(Cannabis, synthetic cannabinoids, and psychosis risk: What the evidence says )〕〔(【引用サイトリンク】title=Medscape: Medscape Access )〕 Synthetic Cannabis is stated to be more toxic to the brain and more addictive than regular cannabis. 〔http://www.forbes.com/sites/alicegwalton/2014/08/28/6-reasons-synthetic-marijuana-spice-k2-is-so-toxic-to-the-brain/〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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